Skip to main content
Quick Answer

What Is Modifier 25?

Modifier 25, defined by the AMA CPT, indicates a significant, separately identifiable evaluation and management (E/M) service performed by the same physician on the same day as another procedure or other service.

  • Audit your Modifier 25 utilization rate against specialty benchmarks.
  • Dermatology, cardiology, and orthopedic specialties commonly see 25-40% of E/Ms with Modifier 25 — anything materially above that range invites payer audits and potential takebacks.
  • Document the separate E/M rationale clearly in the encounter note.
Modifier

Modifier 25

Also known as: Significant, Separately Identifiable E/M Service Modifier

Modifier 25, defined by the AMA CPT, indicates a significant, separately identifiable evaluation and management (E/M) service performed by the same physician on the same day as another procedure or other service.

Definition

Per the AMA CPT manual, Modifier 25 is appended to an E/M code (99202-99215, 99221-99239, etc.) when the physician performs an E/M service that is significant and separately identifiable from another procedure or service performed on the same day. Documentation must support both the E/M and the procedure as distinct services — the E/M cannot simply be the pre/post work routinely included in the procedure (the global package). CMS, OIG, and major commercial payers have repeatedly flagged inappropriate Modifier 25 use as a top audit target; documentation must clearly demonstrate the separate medical decision-making.

Example

A patient presents to dermatology for an evaluation of a new rash and concerns about hair loss. During the visit, the dermatologist also removes a previously identified seborrheic keratosis (CPT 17000). The E/M (CPT 99213) for evaluating the rash and hair loss is separately identifiable from the lesion removal — append Modifier 25 to 99213.

Common Misconceptions

Modifier 25 is not appropriate for the routine pre-procedure assessment that is included in any procedure's global period. The E/M must address a separate problem or rise to a level of complexity beyond the pre/post work intrinsic to the procedure. Same-day E/M billed alongside every procedure is a documented OIG audit target.

Practical Application

Audit your Modifier 25 utilization rate against specialty benchmarks. Dermatology, cardiology, and orthopedic specialties commonly see 25-40% of E/Ms with Modifier 25 — anything materially above that range invites payer audits and potential takebacks. Document the separate E/M rationale clearly in the encounter note.

№ 99 The Closing Argument

Need help with billing?

If this term is showing up in your denials, EOBs, or A/R aging, we can help. Get a free billing audit and we will trace the issue to its root cause.

Free · No obligation · Typical audit 3–5 days &